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In rat models of inflammatory bowel disease, the peptide reduced inflammation, promoted mucosal healing, and improved intestinal barrier function

In addition, among the fusion proteins, nGLP1-DARPin had a higher binding affinity to HSA (G = 9.2 kcal mol 1 ) compared to the mGLP1-DARPin-1 (G = 8.1 kcal mol 1 ) and mGLP1-DARPin-2 (G = 8.3 kcal mol 1 ) fusion proteins, which is comparable with the individual DARPin complexed with HSA (G = 9.6 kcal mol 1 )

This allows it to support cognitive function, focus, clarity, and motivation

GIP and GLP-1 receptor antagonism during a meal in healthy individuals