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Additionally, as research is limited and still in development, some healthcare providers prescribing these weight loss medications may be unaware of how these medications affect reproductive health, particularly as to how they must be stopped well before pregnancy due to safety concerns

These alterations collectively impair Nrf2-driven antioxidant and anti-inflammatory responses, resulting in diminished expression of downstream protective enzymes such as HO-1 and GSH ( BL has been shown to promote nuclear translocation of Nrf2, thereby upregulating HO-1 and enhancing the production of key antioxidant enzymes, including GSH, superoxide dismutase (SOD), and NAD(P)H quinone oxidoreductase 1 (NQO1) ( 2 O 2 exposure, compared with controls (Huang et al., 2022)

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Staying active may also help ease some of the tiredness or low energy you might feel with medications like Ozempic