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The study demonstrated that the vildagliptin add-on group exhibited no clinically relevant weight gain and had a lower incidence of hypoglycemia compared with the sulfonylurea group, and the addition of vildagliptin to sulfonylurea could be considered as a treatment option prior to intensification with insulin [118]

2 Overview of tissue distribution and function of MOTS-c Mitochondria are essential components of eukaryotic cells and are organelles for cellular energy production

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