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Specifically, oscillations in H2B monoubiquitination have been associated with the transcriptional cycling of circadian genes, such as PER1 and PER2, indicating that chromatin remodeling through histone ubiquitination is closely aligned with the molecular clock (Tamayo et al., 2015)

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The stomach, adipose tissue, bone, and pancreas all express GIP receptors, and these have also been found in the cerebral cortex, hippocampus, and olfactory bulb, among other parts of the brain [15, 16]