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Long-Term Management and Expectations Over time, the bodys adjustment to tirzepatide often leads to a reduction in side effects like diarrhea and headaches

3.3 Liraglutide improves hepatic steatosis and fibrosis development in lipodystrophic mice Due to an inability to appropriately store lipids, individuals with lipodystrophies typically develop metabolic dysfunction-associated steatotic liver disease (MASLD) which often progresses to hepatic steatosis and fibrosis

Overall, there is still a lack of convincing evidence for the clinical efficacy of functional food actives, and large-scale, high-quality RCTs are urgently needed to facilitate the translation of these actives from the laboratory to clinical applications