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For instance, certain peptides used in bodybuilding, like growth hormone secretagogues (GHS) and growth hormone-releasing (GRHG) agonists, encourage the body to create and release its own natural human growth hormone (HGH), thereby stimulating muscle growth
doi: 10.3390/medicina59101812 11
10.3389/fphar.2020.600175 Summary Keywords anti-inflammatory effects, clinical applications, GLP-1RAs, liver injury, metabolic regulation Citation Hu Z, Tian D, Yang Z, Zhang J, Zhang L, Xu Y and Lu X (2026) The mechanisms of GLP-1 receptor agonists in liver diseases: their multifaceted impact on immune response and metabolic regulation
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HIF-1 activates glycolysis-related genes, including pyruvate dehydrogenase kinase 1 (PDK1), increasing the conversion of glucose to pyruvate and subsequently to lactate by inactivating PDH, which is considered critical for metabolic adaptation to hypoxia [74] [Figure 1F]
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