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MEDI7247 has shown remarkable antitumor activity in hematological malignancies such as AML, MM, diffuse large B cell lymphoma (DLBCL), acute lymphoblastic leukemia (ALL), Burkitt lymphoma, as well as solid tumors including colorectal cancer, small cell lung cancer, and head and neck squamous cell carcinoma (Pore et al., 2018

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Scientific discussion surrounding IGF-1 LR3 often highlights its interaction with IGF-1 receptors and its role within cellular signaling models involving regulated communication processes such as proliferation, differentiation, and metabolic pathway signaling

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