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Most return to their original weight within 2 years of stopping

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It can be used as monotherapy when metformin is inappropriate, or in combination with other glucose-lowering medicinal products, including insulin, when these alone are inadequate

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These often subside with continued use or dose adjustment (starting at 500 mg twice daily with food can improve GI tolerance, then uptitrating to three times daily) (Li et al., 2023)

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and Hims & Hers Health wasn't on the list

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Cleveland Clinic notes that not replacing them can lead to symptoms of dehydration, like fatigue, muscle soreness, and nausea and vomiting

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