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Epitope-Specific Immunotherapy Targeting CD4-Positive T Cells in Celiac Disease: Safety, Pharmacokinetics, and Effects on Intestinal Histology and Plasma Cytokines with Escalating Dose Regimens of Nexvax2 in a Randomized, Double-Blind, Placebo-Controlled Phase 1 Study

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as insulin secretion, the glycolytic and/or lipolytic potential of tissues, gluconeogenesis and likely most aspects of glucose and energy homeostasis have been found defective and implicated in the pathogenesis and/or progression of hypertension and MetS (Katsimardou et al., 2020)