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Joint pain developing after starting B12 may reflect: Pre-existing musculoskeletal conditions becoming more noticeable Concurrent inflammatory or degenerative joint disease Reactions to excipients in certain formulations The natural course of an underlying condition If you experience persistent or worsening joint symptoms after beginning B12 supplementation, it is advisable to consult your GP or healthcare provider

All eyes are now on how payers and policy makers will respond in due course

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Additional treatments may be needed for more severe cases

Roman P, Estvez AF, Miras A, Snchez-Labraca N, Caadas F, Vivas AB, Cardona D (2018) A Pilot Randomized Controlled Trial to Explore Cognitive and Emotional Effects of Probiotics in Fibromyalgia