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These findings suggest that PK activators could be potential novel therapeutic options for management of other hereditary RBC disorders such as HS characterized by excess oxidative stress, perturbation of the glycolytic pathway, and/or relative PK deficiency
In latent infection, the virus is unable to replicate to produce infectious zygotic virus particles, and the genes expressed in latent EBV infection encode eight EBV proteins, two untranslated EBV-encoded small RNAs (EBERs), 25 premicroRNAs, EpsteinBarr nuclear antigen 1 (EBNA1), and two latent membrane proteins (LMP1 and LMP2) 7
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Overall, the recent growth in publications suggests a rapidly expanding interest in this emerging field
Indeed, dopamine, which is higher during mania, increases ROS, and it seems that, during mania and depression, there is a compensatory increase in antioxidant marker levels [151]
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