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Oxidative stress in multiple sclerosis: central and peripheral mode of action
However, it's essential to remember that this is not the time to abandon your hard work
Moving to the ability of metformin to reduce the metastatic potential, it was demonstrated that the drug not only reduced the migration of MTC cancer cells (Klubo-Gwiezdzinska et al., 2012), but also modified the expression of several markers of the epithelial-tomesenchimal-transition (EMT) (Han et al., 2015)
This discovery complements the mutual signaling communication between mitochondrial and nuclear genes and reveals a complex regulatory mechanism of mitochondrial function
Both have the same main ingredient, but they are used for different reasons
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