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In contrast, while CSS-treated mice displayed a similar pattern of habituation as saline-treated mice, there was no significant difference in the duration of investigative behavior between the third and fourth trials on day 7 after the final CSS administration, suggesting a decrease in olfactory sensitivity in the CSS-treated mice

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Also, hookah users had lower lung diffusing capacity and elevated levels of apoptotic endothelial cell microparticles [109]

However, experts are skeptical about the effectiveness of alternative therapies, like acupuncture and hypnosis