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When soluble fiber is fermented by gut bacteria, the resulting short-chain fatty acids bind to FFAR2 receptors on intestinal L-cells and directly trigger GLP-1 release

Soreness and joint pain may linger longer after any sort of strenuous activity, like an afternoon working in your garden or lifting weights at the gym

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Nature 613, 120129

What GLP-1 Medications Do to Your Body GLP-1 receptor agonists work by mimicking a hormone that: Reduces appetite significantly most users eat significantly less food Slows gastric emptying food sits in your stomach longer, making you feel full Affects taste preferences many users lose interest in fatty or sugary foods Creates calorie deficit leading to rapid weight loss The GLP-1 Protein Challenge Most GLP-1 users struggle to eat enough protein because they simply aren't hungry