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3.1.4 Compound 968 Compound 968 is a specific allosteric inhibitor of GAC (Wang et al., 2010)

Animal studies reported bell-shaped curves for DSIP, and in the human work twice-daily dosing did not produce the night-sleep effect that once-daily morning injections did

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These discoveries gain additional significance in light of recent evidence linking ferroptosis induction to enhanced immunotherapy efficacy, where GSH depletion-triggered ferroptosis can boost anti-tumor immunity through promoting the maturation of dendritic cells and the priming of CD8 + T cells [36]