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Normality assumption was examined prior to analysis and data were log transformed when appropriate to ensure normality of distribution

Lifestyle changes weight management, exercise, stress reduction are the foundation of prevention and treatment

Initial clinical trials using drug-impregnated microneedles (exenatide, insulin, lidocaine, fentanyl) show potential advantages of reduced pain relief, better glycaemic control and less dependence on opioids as opposed to traditional oral agents [105, 107]

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The program is $500 per month