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As estradiol levels are responsible for painful uterine contractions of primary dysmenorrhea, through the increase of prostaglandin F2, histamine can also be considered a contributing factor
Ito et al., 2023) (this may be particularly relevant for the destabilization of myelin), synaptic dysfunction (Tu et al., 2014) (this includes impairment of signaling at the axo-myelinic synapse, crucial for survival of the myelinated axon
Tissue repair and tendon healing The most replicated preclinical findings for BPC-157 concern musculoskeletal soft tissue