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Vitamin B12 deficiency is often found in people that have digestive disorders such as Crohns disease or celiac disease, or have had gastrointestinal surgery in the past

Cell 137 , 635646 (2009)

Thus, the dynamic interaction between microglia and astrocytes, mediated by specific cytokine and chemokine signaling pathways, critically determines neuroinflammatory trajectories and influences both degenerative and regenerative processes in CNS disorders (Jha et al., 2019