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The observed increased plasma levels of 3-hydroxybutyrate and acetoacetate in IHD may indicate a metabolic adaptation in response to cardiac ischemia and impaired glucose oxidation, which force the heart toward ketone body metabolism as alternative energy source 48

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Unlike muscles that enjoy rich vascular networks, tendons depend on a sparse collection of blood vessels that struggle to deliver the oxygen, nutrients, and growth factors needed for repair

Without strength training, a disproportionate amount of that weight came from muscle

This contraindication stems from animal studies showing that GLP-1 receptor agonists cause thyroid C-cell tumors in rodents