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However, the high-iron diets or depletion of GPX4 promotes Hydroxyguanosine 8 (8-OHG) release and thus activates the TMEM173/STING-dependent DNA sensor pathway, which results in macrophage infiltration and activation during Kras-driven PDAC in mice ( An emerging oncoprotein, Myoferlin, controls mitochondria structure and respiratory functions, has been associated with a low survival in several cancer types including PDAC

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Bilayer Deformation, Pores, and Micellation Induced by Oxidized Lipids

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where M 1 , M 2 , and M 3 represent the mass of ORI in liposomes (mg), the total mass of ORI added (mg), and the total mass of soybean lecithin, cholesterol and, ORI added (mg), respectively