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Medications that facilitate reductions in alcohol use while achieving broad clinical uptake would fill a critical unmet need. The phase 2, double-blind, parallel-arm trial recruited 48 non-treatment-seeking patients with AUD at an academic medical center in the U.S

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The first was a review looking at the therapeutic potential of butyrate in treating type 2 diabetes

Aside from TRAILRUNNER-ALZ 1, Lilly is also studying the asset in TRAILRUNNER-ALZ 3, a Phase III placebo-controlled trial comprising 1,200 patients with early Alzheimers disease

GI side effects: Continue to decrease over time