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Small steps

Int J Mol Sci 23(8):4162

However, berberine is classified as a dietary supplement, not a prescription medication, which means it has less rigorous regulatory oversight than FDA-approved drugs or medications from licensed 503A compounding pharmacies

This includes adults with an initial BMI of 30 kg/m 2 and above, or 27 to 29.9 kg/m 2 with at least one weight-associated comorbidity (e.g hypertension, dyslipidaemia, obstructive sleep apnoea, cardiovascular disease, prediabetes or T2DM)

Similarly, arrhythmogenic effects of exogenous LCACs have been found to be attenuated by pharmacological inhibition of ECC components, as will be discussed below