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While this new study finds a more modest increase in NAION incidence than was reported in earlier studies, researchers continue to advocate for greater vigilance among healthcare providers prescribing GLP-1 receptor agonists like semaglutide, which is marketed under the brand names Ozempic, Wegovy, and Rybelsus

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The second and third modifications address clearance and stability

Effect of hydroxyethyl starch on drug stability and release of semaglutide in PLGA microspheres