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Expect some reduction in appetite control during the switch

Naltrexone (Apo-Naltrexone/ReVia

Once available, cagrilintide may be particularly suitable for patients who experience significant GI side effects with GLP-1 medications, those seeking an alternative mechanism for appetite control, or as part of combination therapy for enhanced results

For example, GLP-1 enhances L-type Ca 2+ currents through activation of the cAMP-dependent PKA pathway in canine cardiomyocytes [71], whereas when rat hippocampal neurons are pre-incubated with GLP-1 for 24 h, Ca 2+ currents are significantly decreased [58]

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