These were in the cerebellum (ibuprofen [238], paracetamol [239]), the cerebral cortex (diclofenac [240,241], celecoxib [201]), the frontoparietal cortex (concussive brain trauma) [231], the hippocampus and the cerebral cortex (insulin) [242], and the parietal neocortex and the hippocampus (cuprizone [232])
8 Clinical application prospects of DPP1 inhibitors 8.1 Bronchiectasis Bronchiectasis represents a chronic respiratory disease characterized by permanent and abnormal bronchial dilation, usually secondary to recurrent airway infections and inflammation ( Current clinical practice lacks specific therapies approved for treating bronchiectasis, with clinical management primarily relying on empirical treatment strategies including antibiotic use, airway secretion clearance techniques, and bronchodilator application
Qian, R., Ding, L., Yan, L., Lin, M
GHK-Cu copper tripeptide-1 is a naturally occurring compound in the human body that declines significantly with age
Ramasamy R, Yan SF, DAgati V, Schmidt AM (2007) Receptor for Advanced Glycation Endproducts (RAGE): a formidable force in the pathogenesis of the cardiovascular complications of diabetes and aging