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Van Schaik L, Kettle C, Green R, Irving HR, Rathner JA (2021) Effects of caffeine on brown adipose tissue thermogenesis and metabolic homeostasis: a review

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However, high-dose L-carnitine therapy provides a massive amount of fuel for gut bacteria, causing them to produce more TMA than the livers FMO3 enzymes can process at one time [12] [13]