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Diagnosis typically involves blood tests including full blood count (showing macrocytosis), anti-intrinsic factor antibodies (which are specific for pernicious anaemia), and sometimes anti-parietal cell antibodies

Some complications improve with appropriate treatment, but others, such as problems with the nervous system, can be permanent

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GHRH analogs include sermorelin, CJC-1295, and tesamorelin

It doesn't suppress natural hormone production or cause dependency