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This is when dose escalation and building lifestyle changes create the largest caloric deficits

Understanding this distinction is essential for patients considering treatment options for diabetes or weight management

Higher concentrations allow smaller injection volumes, which some patients find more comfortable

Resource use from the oral semaglutide and liraglutide arms of PIONEER 4 was used to inform annual treatment costs, with 100% of patients receiving concomitant metformin in both arms and 26.0% and 25.7% receiving a concomitant SGLT-2 inhibitor in the oral semaglutide and liraglutide arms, respectively