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This conversation should cover: The medical necessity of both treatments The expected duration of prednisolone therapy (short-term versus long-term) Individual risk factors, particularly regarding diabetes or prediabetes Realistic expectations about weight loss outcomes whilst on corticosteroids Monitoring requirements for blood glucose and other metabolic parameters The decision to use both medications should be individualised , weighing the clinical benefits of each treatment against potential complications

However, nonsteroidal anti-inflammatory drugs like ibuprofen already carry a known risk of causing stomach irritation, ulcers, and bleedingespecially when taken on an empty stomach or without food

Current Uses in Weight Loss and Other Medical Conditions Semaglutide is now widely used for weight loss, particularly in people with obesity or those who have struggled to lose weight through diet and exercise alone

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