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Taking into consideration that mutants affected in glutathione biosynthesis exhibited a susceptible phenotype while, under our conditions, none of the tested sulfate transporter mutants did so, the latter did not seem to affect glutathione homeostasis sufficiently to result in increased susceptibility to AITC

Furthermore, if the PSA value of the patients falls within 4-10 ng/ml, also known as the borderline or grey-level, this poses serious concerns in terms of making the correct diagnosis (6)

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Pruritus, a common and distressing symptom, is managed with moisturizers, antihistamines, and other medications like cholestyramine, though many treatments have limited efficacy