injection of 5 IU PMSG (Intergonan
There have been anecdotal reports of some patients using these drugs for weight loss and then presenting with repeated episodes of nausea and vomiting secondary to a condition referred to as gastroparesis, Mahyar Etminan, the studys senior author and an epidemiologist and ophthalmology and visual sciences professor at the UBC Faculty of Medicine, said in a statement
By helping the body manage and recover from stress more efficiently, it can help blunt chronically elevated cortisol levels
Jia R, Hou Y, Feng W, Li B, Zhu J
Key facts about GLP-1-related gastroparesis: How it happens: GLP-1 drugs slow gastric emptying as part of their mechanism, but this effect becomes excessive in some people Whos at risk: Those with pre-existing digestive disorders, prior gastric surgery, long-standing diabetes, or elderly patients face higher risk Timeline: Symptoms can appear at any point during treatment, especially during dose increases Reversibility: Most cases improve after dose reduction or medication discontinuation, with recovery taking days to several months Management options: Dietary changes (smaller, low-fat meals), slower dose escalation, supportive medications, or temporary drug cessation Seek immediate medical attention for severe vomiting, dehydration signs, intense abdominal pain, or blood in vomit or stool