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More recently, nanocarriers have been engineered to co-deliver therapeutic genes, such as p53, regulatory RNAs (siRNA and miRNA targeting PD-L1, survivin, VEGF, B-cell lymphoma 2 (Bcl-2), and others), and naturally occurring cytolytic peptides, thereby enhancing therapeutic efficacy through gene silencing, apoptosis induction, and immune modulation (Li X

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Trauma, surgery, and other injuries can lead to the loss of the skin barrier, for which conventional wound management strategies, such as gauze and antibiotics, are limited [3]

doi: 10.1016/j.ccell.2022.02.003 111 ZhaoMvan StratenDBroekmanMLDPratVSchiffelersRM