In practice, the challenge is rarely just "can GSH react?"it is whether the conjugation route will give the desired attachment site, manageable impurity profile, acceptable stability, and data that clearly distinguish the target product from free glutathione, oxidized material, and positional isomers
A clinical study has demonstrated that 11CGln is well tolerated by patients with metastatic colorectal cancer (CRC) and can be visualized noninvasively in multiple organs, including the lungs, brain, and bones (75)
Proper hand hygiene helps prevent infections
For true cellular protection, taking capsules or liposomal forms internally is significantly more effective
Thus, measuring the activity of this enzyme is an indicator of oxidative stress