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Stat Appl Genet Mol Biol

In PD, early GSH depletion in the substantia nigra precedes dopaminergic neuron loss, suggesting that redox dysfunction may be an inciting event that leads to eventual neuronal damage ( 2 Mechanisms of redox regulation in the CNS 2.1 GSH as an antioxidant in the brain The brain, being one of the most metabolically active organs in the body, requires a large share of oxygen relative to its mass

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Vitamin C, or ascorbic acid, is perhaps the most famous vitamin on the planet

As 70% of spliced Ubx-targets are exclusively differentially spliced in the embryonic mesoderm 21 , this mechanism could be crucial for Ubx morphogenetic function during muscle development