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Following the dose-escalation schedule in the product SmPC is important to minimise these effects, and several practical strategies can help manage digestive symptoms effectively

Dopamine manipulation affects response vigor independently of opportunity cost

For example, the U87-MG glioma that was found resistant to CR when grown as a subcutaneous xenograft in NOD-SCID mice 63 was responsive to CR when grown orthotopically in mice of a different genetic background

NICE guidance supports individualised treatment approaches for type 2 diabetes and obesity, emphasising shared decision-making between patients and clinicians

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