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In addition to the PI4KA and PI4KB encoded phosphatidylinositol 4-kinases, humans express two additional PI4K encoding genes

b) Dyslipidemia Dyslipidemia is one of the common complications of T2DM as a result of insulin resistance [82]

They work, but their origin raises real questions around immunological safety, sterility, ethical sourcing, and regulatory oversight, and they tend to be less stable