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The effect builds slowly, over months or years, until it shows up as fatigue in someone already managing insulin resistance or PCOS with the same drug

If you are currently taking medication particularly for thyroid conditions, epilepsy, or blood clotting it is best to check compatibility first

It adds that some patients also experience relative dehydration or electrolyte shifts that compound how tired they feel

doi: 10.1016/j.jpsychores.2021.110525 27 Guillen-BurgosHFGalvez-FlorezJFMoreno-LopezSGonzalezIGuillenMAnayaJM

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