While it is not clear if this risk translates to humans, semaglutide carries a warning and is contraindicated in individuals with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2
Compounded semaglutide is a custom-made version of the medication, prepared by specialized compounding pharmacies
Distribute this across three meals, targeting 30-40 grams at each meal
selection should consider presence of cardiovascular disease, heart failure, or chronic kidney disease DPP-4 inhibitors (such as sitagliptin or linagliptin) oral agents with a different mechanism Insulin therapy particularly if glycaemic control is inadequate with oral agents Pioglitazone may be appropriate in selected patients without heart failure Sulfonylureas (such as gliclazide) though associated with hypoglycaemia and weight gain Your diabetes specialist or GP will conduct a comprehensive review of your treatment plan, considering factors such as HbA1c targets, cardiovascular risk profile, renal function, and personal preferences
Side Effects: Both have similar side effect profiles, primarily gastrointestinal issues
