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[] Increased activity of microglial cells (inflammatory processes, phagocytosis, disruption of the bloodbrain barrier and increased synthesis of oestrogen) was linked to increased ROS and unstable behaviours in mice

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Likewise, while ghrelin has the potential to be a useful treatment for cancer cachexia [14], strategies for inhibiting ghrelin signaling have thus far not produced viable pharmacotherapies for obesity, but this is an ongoing area of research [15, 16]

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Liraglutide, a long-acting human glucagon-like Peptide-1 analog, given as monotherapy significantly improves glycemic control and lowers body weight without risk of hypoglycemia in patients with type 2 diabetes