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These observations indicate that GSH-dependent thiol modifications regulate necroptosis at multiple hierarchical levels, from upstream checkpoint proteases to terminal membrane-disrupting effectors

Myeloperoxidase functions as a major enzymatic catalyst for initiation of lipid peroxidation at sites of inflammation

Heavy metal exposure is a potentially harmful factor in male sperm production and fertility (52)

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Biochem J 348(3):607614 Pacholec M, Bleasdale JE, Chrunyk B, Cunningham D, Flynn D, Garofalo RS et al (2010) SRT1720, SRT2183, SRT1460, and resveratrol are not direct activators of SIRT1