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"Tirzepatide versus Insulin Glargine in Type 2 Diabetes and Increased Cardiovascular Risk (SURPASS-4): A Randomised, Open-Label, Parallel-Group, Multicentre, Phase 3 Trial." The Lancet, 2021, 398(10313), 1811-1824

To give you an idea, here are just a few of the more common, and serious, health issues that are linked to being overweight and obese: Type 2 diabetes Cardiovascular disease, including high blood pressure and heart disease Sleep apnea Arthritis Depression Fatty liver disease Gallbladder disease Fertility issues Low testosterone Sexual dysfunction If youre overweight, youre at far greater risk for developing these conditions than someone of healthy weight

Clinical Diabetes : A Publication of the American Diabetes Association, 40 (3), 265269

Se was also negatively correlated with Cu in women with second-trimester induced abortion resulting from neural tube defects [54]

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