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Cyclodextrins may include hydrophobic molecules into their internal cavity, increasing the solubility and thus the oral bioavailability of these drugs [12]

Finally, the new tissue remodels into functional architecture

First, cell-type specificity: future studies should employ single-cell omics, spatial transcriptomics, and ligand-modified nanocarriers to map and manipulate ferroptotic responses in specific vascular cell types, particularly VSMCs, endothelial cells, and macrophages, to ensure selective targeting while minimizing systemic oxidative and immune side effects

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