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In one study, a 500mg daily dose led to better performance on various memory tests compared to a placebo.14 In another, doses of 500mg and 2,000mg of Cognizin boosted brain ATP levels and accelerated brain membrane formation.78 Focus Support also adds in: Rhodiolife Rhodiola rosea extract (5% rosavins, 1.8% salidrosides): 350mg Phosphatidylserine (50%): 300mg KSM-66 Ashwagandha: 300mg N-Acetyl L-tyrosine (NALT): 200mg L-Theanine: 160mg Lions Mane extract (20:1): 100mg Caffeine (Coffeeberry organic extract): 80mg Saffron extract (2% safranals): 30mg Pyrroloquinoline quinone (PQQ): 20mg Vitamin B3: 16mg Vitamin B5: 5mg Vitamin B6: 2mg Vitamin B9: 400mcg Vitamin B12: 2.4mcg The result is a cognitive formula that addresses focus, memory, mood, and long-term brain health in a single daily serving

7 Researchers from the 2020 study also noted that the increase in vitamin B12 was likely unrelated to typical dietary intake or standard supplementation because food and supplements generally do not substantially affect plasma B12 concentrations

After donating its methyl group, SAMe is converted into homocysteine

You don't overshoot as easily

From a mechanistic standpoint, there's no basis for a pharmacological interaction