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When GLP-1 medications activate these receptors, they may: Reduce the pleasurable effects of alcohol Decrease motivation to seek alcohol Lower overall reward-seeking behavior Help regulate impulse control A large Swedish study of approximately 228,000 people with alcohol use disorder found that those taking GLP-1 medications were less likely to be hospitalized for alcohol-related issues

Energy production and mitochondrial function A study published in the Journal of Nutritional Biochemistry examined niacinamide supplementation in obese subjects and found that it reprogrammed adipose cellular metabolism and increased mitochondrial biogenesis

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