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GLP-1 medications can cause GI side effects

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Gartlehner G, Gaynes BN, Amick HR et al

Patients with the following characteristics often see the strongest improvements: Rheumatoid arthritis Psoriatic arthritis Osteoarthritis of the knees or hips Obesity or insulin resistance Chronic fatigue Long-term steroid use Difficulty losing weight despite trying Who Should Avoid GLP-1