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Role of ERp46 in -cell lipoapoptosis through endoplasmic reticulum stress pathway as well as the protective effect of exendin-4

Participants were either infused with saline or NAC at a dosage of 150 mgkg-1

Both SMAD inhibitors and cyclopamine were present in the media until day 9

With this acquisition, Roche aimed to strengthen its metabolic disease franchise by gaining access to Carmots advanced portfolio, particularly a phase-2-ready dual GLP-1/GIP receptor agonist, thereby enhancing its competitive position in both obesity and diabetes markets

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