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The research shows weight loss of 10 to 12 percent with cagrilintide alone, and when combined with semaglutide in the CagriSema protocol , results exceed 22 percent body weight reduction over 68 weeks

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10.1002/cne.902710405 52 KanoskiS

While other multi-agonists that target a variety of receptors have been explored, this specific approach has not been utilized in any previous studies

And Y1 receptor antagonists could also prevent the prohypertensive effect of NPY and possibly augment the antihypertensive effects of DPP-4i