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Common reactions include: Bloating and gas Diarrhea Decreased appetite Metallic taste in mouth A concern with long-term metformin use is vitamin B12 deficiency [20]

sporadic shortages of weekly GLP-1 drugs (widely reported in 20232025 due to surging demand) have highlighted how just-in-time production struggles to keep up

Clinical trials demonstrate average weight loss of 10 to 15% of total body weight over 68 weeks at the 2.4 mg weekly dose

Fernstrom JD, Fernstrom MH