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Despite its widespread use in cell culture studies, SLC7A11 inhibitor Erastin cannot be used for animal studies due to its poor metabolic stability and low solubility in vivo [13]

It is used to study angiogenesis, cellular repair mechanisms, and peptide signaling pathways

Stable ATP binding mediated by a partial NBD dimer of the CFTR chloride channel

Some research shows tissue healing benefits within a few days in small animal studies, while human research use may show improvements over 12 weeks

Correction of HR estimates and 95% CI for bias due to outcome misclassification was carried out according to the Brenner and Gefellers methodology [25]