Source: Rosenstock et al., The Lancet , June 6, 2026 (TRANSCEND-T2D-1)
Once that muscle percentage hits a certain low point, the body may resist further weight loss to protect itself. While the results needs to be confirmed through more research, especially research in people, the findings highlight a vital need for clinicians to help their patients preserve muscle mass through exercise or nutrition while the patients are on GLP-1s
[4] Researchers suggest that should Tesamorelin bind to the GHRH receptor, it may cause structural changes in the receptor, activating intracellular signaling pathways
These are prescribed selectively and monitored closely
The evidence is thin, the regulatory category is food, and serious people roll their eyes at the entire nutraceutical shelf